A niche CRO by choice


Appletree was founded in 2002 by Dr. Georg Mathis. It has steadily grown into an international business. Appletree has its headquarters in Switzerland and a European subsidiary in Luxembourg. Affiliates in several European countries complement the workforce of 20. Appletree is privately owned and AAA – rated.


At Appletree we believe in focusing on what we know best. We have specialized in two areas of contract services: Clinical research and regulatory affairs. Our core business is the development of ophthalmological medicines and medical device investigations. Appletree is the only contract research organisation in Europe with the combined expertise of medical devices and eye care.


News & Events

Appletree CI Group AG offers biostatistics and data management

We proudly announce that brunner & hess software AG, a Swiss company focused on biostatistics and data management is now a part of the Appletree CI Group AG.


Visit us at ARVO 2014

Appletree CI Group will be present at the ARVO from 04 – 08 May 2014 in Orlando FL. We will be happy to meet you at booth MS 15.